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Figure 5: (a): Pityriasis rubra pilaris; the stained specimen showed discrete foci of lamellar hyperkeratosis filled with keratin plugs, suprapapillary hypergranulosis, acntholysis, irregular elongation of rete ridges and perivascular inflammatory lymphocytic infiltrate (H and E, ×200). (b) It showed positive (2+) Wnt5a expression in epidermis (DensityDistribution Score was 24.10) and positive (2+) expression in dermis (DensityDistribution Score was 1.11) (DAB, ×200). (c) Area percentage of Wnt5a expression in epidermis (1.07) and dermis (22.71) (×200). (d) Optical density of Wnt5a expression in epidermis (1.04) and dermis (1.10) (×200) 
