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Year : 2018  |  Volume : 5  |  Issue : 1  |  Page : 48-50

Syringofibroadenoma arising adjacent to verrucous carcinoma: Is it a reactive process, malignant transformation, or collision tumor?

1 Department of Pathology, University of Massachusetts Medical School, Worcester, MA, USA
2 Department of Orthopedics, University of Massachusetts Medical School, Worcester, MA, USA

Correspondence Address:
Dr. Kristine M Cornejo
Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Warren 831B, Boston, MA 02114
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdpdd.ijdpdd_34_17

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Eccrine syringofibroadenoma (ESFA) is a rare, benign tumor showing acrosyringeal or sweat gland differentiation with variable clinical presentations, but distinct histopathological features. Rarely, ESFA coexists with a malignancy such as a squamous cell carcinoma or porocarcinoma. Herein, we report the first case of an ESFA associated with a verrucous carcinoma in a 46-year-old female on the right foot. It is unclear whether it represents a reactive process, a malignant transformation or a collision tumor. We recommend ESFA be completely excised if possible or closely followed given its association with a developing carcinoma.

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