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   2016| January-June  | Volume 3 | Issue 1  
    Online since June 14, 2016

 
 
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ORIGINAL ARTICLE
Role of histochemical stains in differentiating hemangioma and vascular malformation
Ruchir Jitendra Patel, Archana Chirag Buch, Shirish S Chandanwale, Harsh Kumar
January-June 2016, 3(1):1-6
DOI:10.4103/2349-6029.184009  
Background: Benign vascular lesions such as vascular malformation and hemangioma at times pose difficulty in diagnosis both for clinicians and pathologists. Vascular malformations are difficult to treat while hemangiomas resolve spontaneously in most instances. There are instances when vascular malformations, especially arteriovenous malformations (AVMs) have been misdiagnosed as hemangiomas and vice-versa. Clinical and radiological correlation with histopathological confirmation of these anomalies is important for the management of these lesionsAim: The aim was to study the histological characteristics of hemangiomas and vascular malformations and to study the utility of histochemical stains in their diagnosis. Materials and Methods: We retrospectively studied fifty cases retrieved from the records of Department of Pathology which were diagnosed as hemangioma (n=32) and vascular malformation (n=18) on Hematoxylin and Eosin (H and E) stain over a period of 18 months. The cases were analyzed based on findings of histochemical stains such as Verhoeff-van Gieson (VVG), Masson's trichrome (MT), and toluidine blue. Results: After reviewing all the cases with the use of histochemical stains, two of the three cases originally diagnosed as hemangioma turned out to be AVM and one to be venous malformation. An increased number of intra-lesional nerves were found in 16 of 19 cases of AVM and in both cases of venous and lymphatic malformation. Hemangiomas did not show increase in nerve bundles. Mast cells were found to be increased in proliferating hemangiomas and pyogenic granulomas as compared to AVMs. Conclusion: Hemangiomas and vascular malformations should be clearly differentiated to reduce the risk of treatment failure and recurrence. With the use of histochemical stains such as VVG, MT and toluidine blue, the diagnostic difficulty can be reduced and definitive diagnosis is possible.
  5,449 584 -
CASE REPORTS
Clinical and histological comparison of ulcerated lichen planus and chronic cutaneous lupus erythematosus: Aseries of six cases
Meenakshi Batrani, Asha Kubba, Raj Kubba, Kapil Chandra, Krishnakumar Subramanian
January-June 2016, 3(1):7-13
DOI:10.4103/2349-6029.184006  
Cutaneous ulceration as the primary manifestation of chronic cutaneous lupus erythematosus (CCLE) and lichen planus (LP) is uncommon. In the absence of typical lesions, clinical diagnosis is challenging. We report six cases, three each of, CCLE and LP that presented with cutaneous ulcers. A detailed comparison of clinical and histopathological features between two groups was conducted. The statistical significance of comparative features could not be assessed because of small number of cases. In view of clinical and histopathological overlap, diagnosis requires clinico-pathological correlation and ancillary tests including direct immunofluorescence and antinuclear antibodies.
  4,266 273 -
LETTERS TO EDITOR
Chondroid syringoma: Histopathology a cornerstone tool in diagnosis
Kanathur Shilpa, Budamakuntla Leelavathy, Gorur Divya, DV Lakshmi
January-June 2016, 3(1):20-21
DOI:10.4103/2349-6029.184005  
  3,512 261 1
CASE REPORTS
Angiomatoid fibrous histiocytoma
Sunil Yogiraj Swami, BD Baste, VV Narhire, SS Shashikant, GF D'Costa
January-June 2016, 3(1):17-19
DOI:10.4103/2349-6029.184004  
Angiomatoid fibrous histiocytoma[AFH] is a rare soft tissue tumour most commonly occurring in children, adolescents, and young adults. It is considered to be a tumour of intermediate malignancy because of its less aggressive course in contrast to conventional malignant fibrous histiocytoma[MFH]. It accounts for approximately 0.3% of soft-tissue neoplasms. The majority of cases occur in the extremities, are slow growing and are typically painless. We report a case of AFH on the scalp of a 40-year old man, locally recurring within two years of the original operation. AFH is a rare condition with the potential of local recurrence and metastasis. It should be considered in the differential diagnosis of a soft tissue mass in a child or adolescent.
  2,715 251 1
Lipomatous mixed tumor of the skin with predominance of stromal fat
PS Jayalakshmy, Rohini Sebastian, M Feroze, Lovely Jose
January-June 2016, 3(1):14-16
DOI:10.4103/2349-6029.184007  
A rare variant of cutaneous chondroid syringoma, with epithelial differentiation composed of apocrine, follicular, and sebaceous components and showing the presence of predominantly lipomatous stroma, is being reported in a 54-year-old female.
  2,429 269 -
LETTERS TO EDITOR
Pyogenic granuloma: Adiagnostic dilemma
Seema Rani, Preeti Sharma, Arvind Kumar Ahuja
January-June 2016, 3(1):22-23
DOI:10.4103/2349-6029.184002  
  2,062 190 1
Granular cell tumor: An uncommon tumor of Schwann cell origin
Anup Kumar Tiwary, Dharmendra Kumar Mishra
January-June 2016, 3(1):26-28
DOI:10.4103/2349-6029.184008  
  1,901 169 -
Annular elastolytic giant cell granuloma
Naveen Kumar Hvs, Uday Kiran Raja, Bhanu Prakash
January-June 2016, 3(1):24-25
DOI:10.4103/2349-6029.184003  
  1,561 153 -